All the know-how of the group in the surface patterning of antibody and the fabrication and the
characterization of micro/nanobiosensors will be involved in WP4. In the framework ofSensorART
project, the group “Surfaces, Nanotechnology and Biosensors” of Laboratory of Analytical Sciences
is involved in the fabrication of implantable Micro/nanosystems based on the integration of arrays
of micro/nanobiosensors for patients with chronic heart failure. One of the new approach in
SensorART project is the improvement of the response of the impedancemetric measurement by the
immobilization of the specific antibodies on gold micro/nanoelectrodes against different types of
antigen associated with both pro&anti-inflammatory (factor-alpha, Interleukin-1, and Interleukin-6,
interleukin 10, and interleukin 1 receptorantagonist).